Snakeroot extract is an antifungal made from plants in the sunflower family. A 2008 study showed that the remedy is as effective against toenail fungus as the prescription antifungal medicine ciclopirox. For the study, snakeroot extract was applied to the affected area every third day for the first month, twice a week for the second month, and once a week for the third month. You can find snakeroot extract online.
If common remedies do not offer relief within three to four months of consistent use, or if the discomfort worsens, contact your doctor. Extreme infections may require the temporary surgical removal of the nail. A replacement nail will usually grow. As the new nail regrows, it is good practice to treat it with an antifungal cream to prevent reinfection.
If you have diabetes, you may have reduced blood circulation and nerve supply in your feet. You're also at greater risk of a bacterial skin infection (cellulitis). So any relatively minor injury to your feet — including a nail fungal infection — can lead to a more serious complication. See your doctor if you have diabetes and think you're developing nail fungus.
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