For some people, a fungal infection of the nails can be difficult to cure and the first round of medication might not work. The nail infection can’t be considered cured until a new nail that’s free from infection has grown in. Although this indicates that the nail is no longer infected, it’s possible for the fungal infection to return. In severe cases, there may be permanent damage to your nail, and it may have to be removed.
Many podiatrists now consider this an effective treatment, but because it’s new, there’s not enough concrete data to compare with other treatments. Dr. Hinkes raises another concern: “A clinical cure and a mycological cure are two different things. With the clinical cure, you look at the nail and it looks fine. It’s pink and shiny and smooth and it looks great. But if you sample the nail, you might find that there’s mold or fungus there, so it does not have what we call a mycological cure—mycology is the study of fungi.
Topical agents such as amorolfine (Loceryl 5% nail lacquer; applied once or twice a week) and ciclopirox (Penlac 8% nail lacquer; applied daily) are usually prescribed for mild forms of the disease, but the treatment periods are long and their efficacy is somewhat limited due to poor nail plate penetration. These medications kill fungi by interfering with their cell membranes, which leads to their death.
Fungi that are already present in or on your body can cause nail infections. If you have come in contact with someone else who has a fungal infection, it may have spread to you. According to the American Academy of Dermatology (AAD), fungal infections affect toenails more commonly than fingernails because your toes are usually confined to your shoes, where they’re in a warm, moist environment.
The newer drugs are unlikely to cause any liver problems in patients without known liver disease. Blood tests are not needed for once-weekly treatment with fluconazole (Diflucan); however, people taking longer courses often have their liver function tested before starting the medicine and then retested during the course of treatment. It is important to notify the doctor of all side effects while on the medication. You should tell your doctor of all current medications to prevent potential serious drug interactions.
Recognize the signs. Before you can treat toenail fungus, you need to know what to look for. Nail fungus does not necessarily have consistent symptoms. The most common sign that you have nail fungus is tenderness or pain in the nail. Signs of a fungal infection include changes in your nail, such as color changes. The nail will usually get yellow or white streaks on the side of the nail. There is usually due to a buildup of debris under or around the nail, a crumbling and thickening of the outside edges of the nail, a loosening or lifting up of the nail, and nail brittleness.
The first step in treating toenail fungus is using one of the most effective and natural ways to fight candida. In other words, you’ll likely need to make some changes in your diet and adopt a candida diet. The most crucial tactic for treating candida overgrowth is to eliminate what feeds the yeast and candida virus living in your digestive tract in the first place: sugars and conventional grain products.
Dermatophytes — fungus that grows on the skin, hair and nails but don’t penetrate tissues of the body. Athlete’s foot or Trichophyton rubrum is the most common dermatophyte and can actually infect the toenails. Infection can also begin by touching objects that have dermatophytes on them, such as nail clippers, nail files, socks, shoes, shower floors, etc. Dermatophytes are the cause of most fungal toenail infections.
Disclaimer: Individual results may vary. The text on this website is for informational purposes only and should not be used in substitute for the advice of a physician or other medical professional. All statements, opinions, and information on this website have not been evaluated by the Food and Drug Administration. All trademarks or registered trademarks are the property of their respective owners. See full disclaimer. Click here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of the antifungal ingredients referenced based on the expertise of relevant professionals. Never disregard professional medical advice or delay seeking medical treatment due to something you have read or accessed through this website.
Wei, Y.-X., Xu, X.-Y., Xu, & Song, X. (2017). A review of antifungal natural products against the pathogenic fungi causing athletes' foot disease. Current Organic Chemistry, 21, 1–13. Retrieved from https://www.researchgate.net/profile/Xun_Song/publication/319128408_A_Review_of_Antifungal_Natural_Products_Against_the_Pathogenic_Fungi_Causing_Athletes'_Foot_Disease/links/59931c65458515c0ce61efa1/A-Review-of-Antifungal-Natural-Products-Against-the-Pathogenic-Fungi-Causing-Athletes-Foot-Disease.pdf