Onychomycosis does not necessarily require treatment.[3] The antifungal medication, terbinafine, taken by mouth appears to be the most effective but is associated with liver problems.[2][4] Trimming the affected nails when on treatment also appears useful.[2] There is a ciclopirox containing nail polish, but it does not work as well.[2] The condition returns in up to half of cases following treatment.[2] Not using old shoes after treatment may decrease the risk of recurrence.[3]
The newer drugs are unlikely to cause any liver problems in patients without known liver disease. Blood tests are not needed for once-weekly treatment with fluconazole (Diflucan); however, people taking longer courses often have their liver function tested before starting the medicine and then retested during the course of treatment. It is important to notify the doctor of all side effects while on the medication. You should tell your doctor of all current medications to prevent potential serious drug interactions.

Toenail injury: There are two types of injuries that can occur to your toenail. The first is acute trauma where the nail is impacted over and over again as in the case of a runner wearing shoes that don’t fit well. The other thing that can happen is blunt trauma where something falls on your toe such as a heavy object and causes an injury. This injury makes your toenail more susceptible to fungus. It is important in both cases to look after your toenails properly to avoid an infection.
To get rid of toe fungus, apply 100% tea tree oil to the affected area with a cotton swab twice a day. You can also try applying Vick's VapoRub to your toe every night before you go to sleep, which may make the fungus go away. Another home remedy you can try is snakeroot leaf extract, which may clear up the fungus if you apply it to the affected area every 3 days. If home remedies aren't helping, talk to your doctor about getting an oral or topical antifungal medication.
Use soap and water to wash your feet, and dry well, including between toes. Trim your toenails -- straight across -- to keep them shorter than the end of your toe. Make sure the tools you use are clean, too. Wash clippers and files with soap and water, then wipe with rubbing alcohol. You might be tempted to cover up discolored nails with polish, but don't. Your nail bed can't "breathe," which keeps fungus from going away.
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