Efinaconazole (Jublia) is a medication that was approved in 2014. It is a topical (applied to the skin) antifungal used for the local treatment of toenail fungus due to two most common fungal species affecting nails (Trichophyton rubrum and Trichophyton mentagrophytes). Once-daily application is required for 48 weeks. The most common side effects of Jublia are ingrown toenails and application site dermatitis and pain.
Terbinafine can cause gastrointestinal (stomach and bowel) problems and a temporary loss of taste and smell. It can also interact with certain antidepressants and heart medications. Overall, terbinafine has far fewer drug-drug interactions than itraconazole. Nevertheless, it’s still important to tell your doctor if you are taking any other medication. As a precaution, this medication should not be taken during pregnancy or if you are breastfeeding.
Dermatophytes — fungus that grows on the skin, hair and nails but don’t penetrate tissues of the body. Athlete’s foot or Trichophyton rubrum is the most common dermatophyte and can actually infect the toenails. Infection can also begin by touching objects that have dermatophytes on them, such as nail clippers, nail files, socks, shoes, shower floors, etc. Dermatophytes are the cause of most fungal toenail infections.
Efinaconazole (Jublia) is a medication that was approved in 2014. It is a topical (applied to the skin) antifungal used for the local treatment of toenail fungus due to two most common fungal species affecting nails (Trichophyton rubrum and Trichophyton mentagrophytes). Once-daily application is required for 48 weeks. The most common side effects of Jublia are ingrown toenails and application site dermatitis and pain.
Tea tree oil, also called melaleuca, is an essential oil with antifungal and antiseptic abilities. According to the National Center for Complementary and Integrative Health, some small-scale clinical studies showed that tea tree oil might be effective against toenail fungus. To use, paint the tea tree oil directly onto the affected nail twice daily with a cotton swab. Find therapeutic-grade tea tree oil on Amazon.

In some cases of suspected nail fungus there is actually no fungal infection, but only nail deformity. A 2003 source gives a figure of 50%[17] whereas a more recent source claims that fungus is present in 65 to 95 percent of cases.[18] Avoiding use of oral antifungal therapy (e.g. terbinafine) in persons without a confirmed infection is a particular concern because of the possible side effects of that treatment.[17] However, according to a 2015 study, the cost in the United States of testing with the periodic acid–Schiff stain (PAS) was about $148. Even if the cheaper KOH test is used first and the PAS test is used only if the KOH test is negative, there is a good chance that the PAS will be done (because of either a true or a false negative with the KOH test). But the terbinafine treatment only cost $10 (plus an additional $43 for liver function tests). In conclusion the authors say that terbinafine has a relatively benign adverse effect profile, with liver damage very rare, so it makes more sense cost-wise for the dermatologist to prescribe the treatment without doing the PAS test. (Another option would be to prescribe the treatment only if the potassium hydroxide test is positive, but it gives a false negative in about 20% of cases of fungal infection.) On the other hand, as of 2015 the price of topical (non-oral) treatment with efinaconazole was $2307 per nail, so testing is recommended before prescribing it.[18]


Français: se débarrasser d’une onychomycose, Italiano: Liberarsi dall'Onicomicosi, Español: eliminar los hongos de las uñas de los pies (onicomicosis), Deutsch: Zehenpilz loswerden, Português: Se Livrar de Pé de Atleta, 中文: 治疗甲癣, Русский: лечить грибковое поражение ногтя, Nederlands: Van schimmelnagels afkomen, Bahasa Indonesia: Menyingkirkan Jamur di Jari Kaki, Čeština: Jak vyléčit plíseň na nehtech, ไทย: กำจัดเชื้อราที่เล็บเท้า, हिन्दी: पैर के फंगल संक्रमण से छुटकारा पाएँ, العربية: التخلّص من فطريات الأظافر, Tiếng Việt: Điều trị Nấm móng chân
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If you observe any abnormal nail changes it is important to visit your doctor for prompt assessment. In addition to being cosmetically unappealing, OM can also lead to more serious complications, including the possible loss of your nail, bacterial infections, or cellulitis. Speak with your healthcare provider to determine what the best treatment plan is for you.
Fungal nail infections can be difficult to treat. Talk with your doctor if self-care strategies and over-the-counter (nonprescription) products haven't helped. Treatment depends on the severity of your condition and the type of fungus causing it. It can take months to see results. And even if your nail condition improves, repeat infections are common.
Once it takes hold, the bacteria and yeast thrive off of sugar molecules entering the digestive tract through the foods you eat. That’s exactly why you need to eliminate the underlying cause, which is likely stemming from your diet (and possibly also your lifestyle to some degree). This will help ultimately restore your body’s pH balance, improve your immune function and boost the presence of good bacteria in your gut.
If you have diabetes, you may have reduced blood circulation and nerve supply in your feet. You're also at greater risk of a bacterial skin infection (cellulitis). So any relatively minor injury to your feet — including a nail fungal infection — can lead to a more serious complication. See your doctor if you have diabetes and think you're developing nail fungus.
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