Persistent fungal signs can show up slowly but last for years. Getting rid of toenail fungus can take some patience and requires time to fully heal. It can take several months until treatment is successful, but doing things the right way and getting rid of the underlying cause of nail fungus is the only thing that will keep the infection from coming back again.
Medications in tablet form are much more effective at fighting nail fungus than topical treatments are, but they aren’t guaranteed to work and also have more side effects, long treatment durations and possible interactions. (7) Another downside is that they are like putting a Band-Aid on the problem — they’re not addressing why the fungus developed in the first place.
Griseofulvin (Gris-Peg, Grifulvin V, Griseofulvin Ultramicrosize) is an antibiotic prescribed to treat fungal infections such as ringworm of the body, athlete's foot, barber's itch, and fungal or ringworm of the nails. Side effects, drug interactions, dosing, storage, and pregnancy and breastfeeding information should be reviewed prior to taking this medication.
Anti-fungal properties of lavender oil make it an effective remedy for mild cases of toenail fungus.  Apply a few drops of 100% pure lavender essential oil to the infected nails every night and let it soak in while you sleep.  To prevent the oil from rubbing off, you can optionally cover your feet with a pair of wool socks.  Just be sure not to use socks made of synthetic fibers as this will only worsen the infection.  Remember, a nail that looks healthy may still be hiding traces of fungus.  It is best to continue topical treatments such as this one for at least a few weeks after the infection appears to be gone.
Rotate your shoes – Change your shoes often. Even though you may have that favorite pair that you like to wear all the time, it is better for your feet to switch up your shoes from time to time. Even wearing the same pair of shoes two days in a row can elevate your risk for toenail fungus. Place shoes that you are not wearing in an area where they will get plenty of air.
Healing time depends on the type of treatment used. Prevention of a new infection is important. Orthopaedic foot and ankle specialists recommend good foot hygiene with frequent changing of stockings and rotating pairs of shoes to allow them to completely dry between uses. Also, avoid going barefoot in locker rooms and around swimming pools. If you have a pedicure, make sure the nail salon uses sterilized instruments.
Yeast infection treatment depends on the specific kind of infection that is being treated. Skin yeast infections are highly treatable with medicated creams. Medicated suppositories may be used to treat yeast infections in the vagina. Thrush may be treated with a medicated mouthwash or lozenges that dissolve in the mouth. Severe infections or infections in someone with a compromised immune system may be treated with oral anti-yeast medications.
​The American Orthopaedic Foot & Ankle Society (AOFAS) offers information on this site as an educational service. The content of FootCareMD, including text, images and graphics, is for informational purposes only. The content is not intended to substitute for professional medical advice, diagnoses or treatments. If you need medical advice, use the "Find an Orthopaedic Foot & Ankle Surgeon" tool at the top of this page or contact your primary doctor. 
Readily available over-the-counter treatments work well for most nail-bed infections, especially early cases. An advanced toenail fungus infection may require a podiatrist’s intervention. To counteract a serious infection, medical professionals may utilize prescription topical medications, oral medications, and even laser therapy.  Some cases best respond to combination therapy.
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
Take oral medication. The most effective way to get rid of nail fungus is systemic treatment with oral prescription antifungals. Treatment with oral medications can take 2-3 months or longer. Oral antifungal prescription medications include Lamisil, which is usually prescribed with a dose of 250 mg a day for 12 weeks. Side effects can include rash, diarrhea, or liver enzyme abnormalities. This medication should not be used if you have liver or kidney issues.
Fungus can infect the skin and nails of your feet. A fungal infection of the skin is also known as Athlete’s Foot, which causes itching, burning, and flaking. This infection can spread to the toenails if it’s not treated. Both types of foot fungus are extremely contagious, both in your own body as well as to other people through contact. Therefore, it’s essential to treat the infection and prevent its recurrence.
Disclaimer: Individual results may vary. The text on this website is for informational purposes only and should not be used in substitute for the advice of a physician or other medical professional. All statements, opinions, and information on this website have not been evaluated by the Food and Drug Administration. All trademarks or registered trademarks are the property of their respective owners. See full disclaimer. Click here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of the antifungal ingredients referenced based on the expertise of relevant professionals. Never disregard professional medical advice or delay seeking medical treatment due to something you have read or accessed through this website.
Nail fungus is usually harmless. But many people find discolored or thickened nails unpleasant to look at and want to get rid of the fungus as soon as possible. Fungal nail infections can also spread, and may infect other people. Regardless of the treatment you choose, it will take a while until the nail looks normal again. It’s especially important to be patient where toenails are concerned. It can take a year for a healthy big toenail to grow back. Nail fungus can sometimes be very persistent despite treatment. It can also come back after successful treatment.
^ Jump up to: a b American Academy of Dermatology (February 2013), "Five Things Physicians and Patients Should Question", Choosing Wisely: an initiative of the ABIM Foundation, American Academy of Dermatology, retrieved 5 December 2013. Which cites:*Roberts DT, Taylor WD, Boyle J (2003). "Guidelines for treatment of onychomycosis" (PDF). The British Journal of Dermatology. 148 (3): 402–410. doi:10.1046/j.1365-2133.2003.05242.x. PMID 12653730.
Persistent fungal signs can show up slowly but last for years. Getting rid of toenail fungus can take some patience and requires time to fully heal. It can take several months until treatment is successful, but doing things the right way and getting rid of the underlying cause of nail fungus is the only thing that will keep the infection from coming back again.

Before taking action and finding the best nail fungus treatment for you, it is important to note that toenail fungus and skin fungus, such as athlete’s foot, often manifest together. For the best results, both should be treated at the same time to prevent an ongoing infection. You can recognize athlete’s foot by the dry, scaling, peeling skin on the bottom of the feet. Your feet may also itch, or exude a noticeable odor.
Toenail fungus often begins as an infection in the skin called tinea pedis (also known as athlete’s foot). The fungus often starts under the nail fold at the end of the nail. Over time, it grows underneath the nail and causes changes to its appearance, such as a yellow or brownish discoloration. It can also cause thickening and deformity of the toenail. 
Prescription oral antifungals such as terbinafine (Lamisil) or fluconazole (Diflucan) are traditionally used to treat toenail fungus. These treatments are often effective, but they may cause serious side effects ranging from upset stomach and dizziness to severe skin problems and jaundice. This may be why many people try home remedies instead. Here are 10 of these popular at-home treatments.
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