Efinaconazole (Jublia) is a medication that was approved in 2014. It is a topical (applied to the skin) antifungal used for the local treatment of toenail fungus due to two most common fungal species affecting nails (Trichophyton rubrum and Trichophyton mentagrophytes). Once-daily application is required for 48 weeks. The most common side effects of Jublia are ingrown toenails and application site dermatitis and pain.
Creams and other topical medications have traditionally been less effective against nail fungus than oral medications. This is because nails are too hard for external applications to penetrate. It is also cumbersome to adhere to topical medication regimens. Oftentimes, these medications require daily applications for a period of time up to one year to see results. One of the major advantages of topical treatment is the minimal risk for serious side effects and drug interactions compared to oral therapy.
Select shoes that fit right –  Choosing the correct footwear is a must if you want to avoid toenail fungus. Shoes should not touch your toenails at all. Don’t jam your feet into shoes that are too big either – this will cause you to jam your toenail into the front of the shoe causing damage. According to the American Academy of Physicians, the best shoes have a wide toe box.

Do the research before trying this product. I sure wish I had. Any "natural" product insures results with regular use but warns that the process takes weeks and even months, due to slow nail growth. These natural remedy sites also warn that you should never reuse the mixture when reapplying because any contamination with the fungus can "inhibit or create more fungus growth." This cancels out the 2nd step altogether given the redipping of the nail brush. Perhaps this product does work for some people after repeated use for many months. I'd just love to see that truth written in more reviews.


I fully believe in natural remedies as well as safe, pharmaceutical ones. I have all of the ingredients and essential oils necessary to make my own potions, but as a busy, working Mom I chose the easy route of purchasing the potion already made up. I used this religiously for over a month. I cleaned and trimmed my affected 4 toenails constantly through the process. I saw absolutely no results. Yes, the painted on 2nd step does temporarily improve the appearance of the nail instantly, but that's because of the glossy sheen. Any oil will do that. Once soaked in, my nail looked and remained the same. Perhaps my failure was a result of dipping the brush I used on my infected toes and back into the bottle repeated times. Doesn't that seem counter productive given a fast-spreading fungus? They're slowly growing out but the fungus remains in the grow out and my nails are still thin and fragile. I would have given this product one more star with a pat on the back and a "nice try" but the huge number of immediate, 5-star reviews left me with the instant feeling of being mislead. I may have even given it more time with more realistic reviews.
“The medications we use to treat this are expensive and they are not benign,” cautioned Dr. Hinkes. “Lamisil is so powerful it stays in your body six months after you stop using it, and that’s one of the reasons why it works so well. So when we use these medicines, we have to be conscious that we may be affecting a person’s liver, because the liver is the organ that helps to detoxify the body and excretes that medicine.”
You asked for the best nail fungus treatments currently available on the market so we developed a criteria to rank them based upon their most important qualities. We looked past the marketing and at the nail fungus remedies themselves, their ingredients, price, effectiveness, and return policies to develop this simple comparison chart. With your combined feedback, our editors put together the following nail fungus product chart for your convenience:

Flip-flops offer very little protection. The risk of getting splinters or other foot injuries is higher when the feet are so exposed. People with diabetes should not wear flip-flops, because simple cuts and scrapes can lead to serious complications. In addition, many flip-flops provide no arch support. Like ballet flats, they can aggravate plantar fasciitis and cause problems with the knees, hips, or back.


Elizabeth is an experienced freelance writer, specializing in health & wellness, education & learning, family life & parenting, and women's issues. She's been published on Huffington Post, and was a regular contributor to Love Live Health and Daily Home Remedy. Elizabeth is a retired primary school principal and education consultant, with a continuing passion for education and learning. She's familiar with writing newsletters, reports to stakeholders, financial reports, business plans and evaluation reports.
Terbinafine can cause gastrointestinal (stomach and bowel) problems and a temporary loss of taste and smell. It can also interact with certain antidepressants and heart medications. Overall, terbinafine has far fewer drug-drug interactions than itraconazole. Nevertheless, it’s still important to tell your doctor if you are taking any other medication. As a precaution, this medication should not be taken during pregnancy or if you are breastfeeding.
Use tea tree oil. Tea tree oil is a natural anti-fungal. One study showed that tea tree oil may be effective for nail fungus. 18% of patients who used tea tree oil twice daily for 24 weeks were cleared of the infection.[13] To treat nail fungus with tea tree oil, use a 100% solution because lower concentrations have not been proven to be effective for this particular infection.[14]
​The American Orthopaedic Foot & Ankle Society (AOFAS) offers information on this site as an educational service. The content of FootCareMD, including text, images and graphics, is for informational purposes only. The content is not intended to substitute for professional medical advice, diagnoses or treatments. If you need medical advice, use the "Find an Orthopaedic Foot & Ankle Surgeon" tool at the top of this page or contact your primary doctor. 
Okay guys. Lets get real ... Fungus happens. I have struggled with this problem for YEARS and it's gross. I was so thankful when I ran across this product and decided to give it a whirl. and WOW I am really impressed by the results. I have been using it for 2 months now and my fungus is totally cleared up. I haven't had clear toenails since I was a kid. Thank you so much! You have a lifetime customer in me now!
One of the more interesting remedies for toenail fungus is organic cornmeal.  Corn naturally hosts a form of fungus that is harmless to the human body but deadly to Candida – the most common fungal parasite that causes infections in people.  In a container big enough to fit your foot (or both feet if needed), mix one cup of cornmeal and about two quarts of water.  Allow the cornmeal to soak in the water for at least one hour then submerge the infected foot (or feet) in the mixture for a half hour or more.  While the frequency of use for this remedy is up for debate, sources have reported success with treatment performed as seldom as once per week.  Others say to perform it daily.  Because cornmeal is totally harmless to skin and nails, realistically the treatment can be repeated as often as you like.

Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.


An imbalance of healthy micro-flora in the body can also be a big cause of fungal overgrowth like onychomycosis. Be sure to partner a good probiotic supplement with your choice of toenail fungus remedy.  Thriving, healthy gut bacteria hinder the growth and spread of parasitic fungi and other microbes by limiting their available living space.  Also, lactobacillus bacteria found in most probiotic supplements actually secrete a biproduct that is poisonous to Candida.  Just make sure that your supplement contains no sugar or artificial fillers that may inadvertently feed the unwanted fungus.

Infected nails are usually thicker than normal and could be warped or oddly shaped. They can break easily. Nails with fungus might look yellow. Sometimes a white dot shows up on the nail and then gets bigger. When fungus builds up under your nail, it can loosen and even separate the nail from the bed. The fungus can also spread to the skin around your nail.
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