Snake root extract comes from a plant in the sunflower family. A 2008 study conducted by the Centro de Investigación Biomédica del Sur and published in Planta Med, found that applying the extract to the affected nail over three months was more effective than treatment with the prescription anti-fungal Penlac (ciclopirox). Like natural remedies? Here are some more options.
You may first notice a fungal toenail infection as a small white or yellow spot on the tip of your toenail, especially the big toe. As the infection progresses, the toenail can become yellow, brittle—even crumbly—and thick and uneven-looking. In the worst fungal infections, the toenail separates from the nail bed. This is called onycholysis. As fungal infections worsen, the nail beds can be tender to the touch and quite painful. Sometimes women try to pretend the pain is “normal” and ignore it altogether.
Onychomycosis – commonly known as toenail fungus – is characterized by inflammation, pain, and swelling of the toe, as well as yellowing, thickening, and crumbling of the nail itself.  Toenail fungus can be the result of abnormal pH of the skin, continuous exposure to moisture, wearing synthetic socks, compromised immune system, sweat build-up in shoes, poor foot hygiene, or weak circulation such as that caused by diabetes.
One of the best remedies for toenail fungus, apple cider vinegar can be used topically, internally, or both. Mix one part ACV and one part Epsom salts with six parts hot water.  Let the water cool so that it is still warm to the touch, but not so hot as to be damaging to your skin.  Soak feet up to twice daily for at least thirty minutes to kill fungus.  Mix two tablespoons of organic apple cider vinegar with eight ounces of warm water and add a teaspoon of honey to sweeten the beverage.
The vesiculobullous type of athlete's foot is less common and is usually caused by T. mentagrophytes and is characterized by a sudden outbreak of itchy blisters and vesicles on an erythematous base,[7] usually appearing on the sole of the foot. This subtype of athlete's foot is often complicated by secondary bacterial infection by Streptococcus pyogenes or Staphylococcus aureus.[13]
For fungus infection, there are plenty of options. Many medications are available, including miconazole (Micatin, Zeasorb powder), econazole (Spectazole), clotrimazole (Lotrimin), terbinafine (Lamisil), naftifine (Naftin), butenafine (Mentax), ciclopirox (Loprox), ketoconazole (Nizoral), efinaconazole (Jublia), luliconazole (Luzu), sertaconazole (Ertaczo), sulconazole (Exelderm), and tolnaftate (Tinactin). Ask your health care professional or pharmacist for a recommendation. It is difficult to know which of these drugs is most effective since they have not been tested against each other. Cost is probably the most significant differentiating factor, and many are available without a prescription. Treatment for athlete's foot should generally be continued for four weeks or at least one week after all of the skin symptoms have cleared.

Vicks VapoRub is a topical ointment. Although designed for cough suppression, its active ingredients, camphor and eucalyptus oil, may help treat toenail fungus. A 2011 study found Vicks VapoRub had a “positive clinical effect” in the treatment of toenail fungus. To use, apply a small amount of Vicks VapoRub to the affected area at least once a day.
Red or black nails due to a hematoma, or blood under the nail, usually occur from trauma (like whacking yourself on the thumb with a hammer). The discolored area will grow out with the nail and be trimmed off as you trim your nails. If you have a black spot under your nail that was not caused by trauma, you may want to see a dermatologist or a podiatrist if it involves a toenail to make sure it is not melanoma (a type of skin cancer associated with pigmented cells). A simple biopsy can rule out malignancy (cancer).
Multiple fungi species can infect the nail. Fungus grows well in warm, moist environments such as showers. Fungus infection is one of the few foot problems that affect more men than women, perhaps because more men walk barefoot in locker rooms. Age is a factor, too. Half the sufferers are people older than 70. Other risk factors include having certain medical conditions such as diabetes, vascular insufficiency and malnutrition.
How to get rid of a yeast infection Many treatments are available for a yeast infection, some of which a person can administer at home. This article looks at 8 home remedies, including probiotics, natural yogurt, and tea tree oil. However, these remedies are not suitable for everyone. Also, learn about symptoms, prevention, and when to see a doctor. Read now
I can tell you my own mother struggled with toenail fungus on her big toe for over 10 years, and the reason why she originally got it and then continued to struggle with this fungus was the chemotherapy she went through when diagnosed with breast cancer years ago. After going through chemo, she had systemic yeast and candida issues and then developed the toenail fungus. The exact treatment I detail below is what we used with her to successfully erase her fungus.
Walking barefoot in public places: Sure, taking your shoes off may feel great but it can also lead to toenail fungus. Toenail fungus starts when moisture gets trapped under the nail. This can easily happen when you walk barefoot.It is also easy to pick up toenail fungus from walking in public places as fungus can survive for up to 6 months on surfaces. The most common public places where you can pick up toenail fungus include swimming pools and public showers. Protect yourself by wearing sandals in public pool areas and public showers.
Other risk factors include perspiring heavily, being in a humid or moist environment, psoriasis, wearing socks and shoes that hinder ventilation and do not absorb perspiration, going barefoot in damp public places such as swimming pools, gyms and shower rooms, having athlete's foot (tinea pedis), minor skin or nail injury, damaged nail, or other infection, and having diabetes, circulation problems, which may also lead to lower peripheral temperatures on hands and feet, or a weakened immune system.[11]

Do the research before trying this product. I sure wish I had. Any "natural" product insures results with regular use but warns that the process takes weeks and even months, due to slow nail growth. These natural remedy sites also warn that you should never reuse the mixture when reapplying because any contamination with the fungus can "inhibit or create more fungus growth." This cancels out the 2nd step altogether given the redipping of the nail brush. Perhaps this product does work for some people after repeated use for many months. I'd just love to see that truth written in more reviews.
The final step to removing fungal and yeast infections is taking supplements, such as the probiotic supplement that I mentioned above. A quality probiotic supplement will help you get rid of the yeast and candida in your system that’s truly causing your toenail fungus. I personally recommend a probiotic supplement that has at the very least 10+ strains of probiotics with at least 15 billion CFUs.
If you have diabetes or a weakened immune system, treatment is especially important. After getting a fungal nail infection, people who have diabetes have an increased risk of developing sores that do not heal. Sores that do not heal can lead to a serious health problem. It’s important to see a dermatologist (or other doctor) at the first sign of a nail problem. A dermatologist can tell you whether you have a nail infection or something else. 
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