Orange essential oil is another natural anti-fungal that can be applied daily to toenails in order to cure an infection. Apply a drop of Plant Therapy Orange Oil on nails and between toes. Let the oil soak in for at least one hour. Orange oil may be too strong for people with sensitive skin. If you find this is the case for you, dilute the oil with an all-natural carrier such as olive oil. Also, because citrus allergies are somewhat common, it is recommended to test orange oil on a spot of healthy skin before applying it to infected nails. (Many health and wellness stores have open ‘testers’ of their products for just such a purpose.)
Oral/combination therapy. Some studies have shown that taking antifungal pills and applying antifungals to your nails can be more effective than using either treatment alone. Oral medications can typically treat toenail fungus in three months. In stubborn cases, topical and oral medications may be combined to provide the best possible treatment. Oral medications must be prescribed by your physician or health care practitioner.